Tabex is an original Bulgarian preparation of plant origin, intended for the treatment of tobacco smoking.
The preparation is developed on the basis of the
alkaloid Cytisine, contained in the plant Cytisus laborinum L.
(Golden Rain acacia).
The broad clinical studies carried out,
show that the therapy with the preparation Tabex results in
giving up smoking in more than 57% of the patients.
In the human body, Cytisine plays the role of nicotine substitution substance, and reduces the period of interaction of the received nicotine with relevant nicotine receptors, i.e. the specific substance cytisine "substitutes" nicotine, acting on the same receptors, thus preventing the appearance of abstinence syndrome. This results in a gradual reduction and suspension of the psychic and physical dependency to nicotine in smokers. Cytisine possesses a structure and mechanism of action that are similar to those of nicotine, but it has much lower toxicity.
Tabex manifests one of the best results to date for the group of preparations, intended for tobacco smoking therapy. Cytisus laborinum L the Tabex source plant aka Golder Rain acacia. Tabex is very well tolerated, and when applied in therapeutic doses, allows a gradual giving up of smoking without any side effects.
The total giving up of smoking should take place not later than the fifth day after the beginning of the therapy. Supplied in a package of 100 filmtablets of 1.5 mg Citysine.
Tabex recommended therapeutic scheme
|Day of Treatment||Intake Intervals||Total Daily Tablets|
|Day 1 to 3||1 tablet every 2 hours||6 tablets daily|
|Day 4 to 12||1 tablet every 2.5 hours||5 tablets daily|
|Day 13 to 16||1 tablet every 3 hours||5 tablets daily|
|Day 17 to 20||1 tablet every 4 hours||3 tablets daily|
|Day 21 to 25||1 tablet every 6 hours||2 tablets daily|
|Click here for Important usage details|
PHYSIOLOGICAL MECHANISMS OF THE ORIGIN
OF NICOTINE DEPENDENCE AND ITS OVERCOMING!
Paun D. and Franze J. have studied and analyzed the physiological prerequisites for the harmful habit of smoking. After inhalation of a cigarette by a person with low blood pressure and possibly also with low blood sugar content, for about 20 minutes nicotine increases the blood pressure and the blood sugar level. In persons with normal blood pressure and blood sugar values, the nicotine in the blood leads to hormonal and vegetative changes in the organism, while the discontinuation of smoking leads to a decrease in the blood pressure and blood sugar values. That is why, nicotine abstinence is clinically manifested with exhaustion, tiredness, poor concentration and irritability (abstinence manifestations), which provokes a strong craving for nicotine. The abstinence syndrome can be controlled by restoring the normal blood pressure and blood sugar values by means of analeptics, tranquilizers and mostly by means of specific drugs , such as cytisine, lobeline, etc. These specific drugs "replace" nicotine by acting on the same functional receptor constellations.
Tabex is a drug of choice of treatment of chronic nicotinism. It is particularly appropriate for treatment of risk groups of smokers with health problems on the part of the cardiovascular and respiratory systems, as well as smokers professionally subjected to tension and stress that are predisposed to seek a "false comfort" in nicotine or other drugs causing dependence.
Advanced atherosclerosis, some forms of schizophrenia, pheochromocytome, conditions connected with severe impairment of the cardiovascular system and malignant hypertension.
Additional Important Usage Information
Tabex is administered orally in a dose of 1 tablet every 2 hours (6 tablets daily) for 3 days at corresponding reduction of the number of smoked cigarettes.
The treatment proceeds according to the following scheme:
Complete discontinuation of smoking must occur by the 5th day of treatment.
As antidotes at overdose of the preparation Tabex one may use tranquilizers (anticonvulsive effect) and antihypertensive drugs (decrease of the blood pressure).
The high doses may provoke nausea, vomiting, dizziness, tachycardia and muscle weakness. These effects pass quickly after the dose is decreased.
The analeptic effect of cytisine decreases during combined therapy with antituberculosis drugs (PASA, streptomycin, etc.).
The drug should be administered carefully to patients with exacerbated peptic ulcer. After completing the treatment course, the patients should refrain from smoking even one cigarette, in order to obtain a lasting effect.
Filmtablets of 1.5 mg in packages of 100.
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